Association of proteinurai in children with acyanotic congenital heart disease and pulmonary hypertension in a Tertiary University Hospital in Northwest Iran

ABSTRACT

This study was performed to detect the severity of proteinuria in children with cyanotic pulmonaryhypertension. Twenty children suffering from pulmonary hypertension due to acyanotic heart disease evaluated for proteinuria. They were divided into two groups of equal less than two amd more than two years old, because of the difference in proteinuria ratio in these two groups. Association of proteinuria with age, hematocrit, mean pulmonary arterial pressure and tricuspid regurgitation were evaluated. Although there was not any case of proteinuria in nephrotic range but significant roteinuria was observed in 2 out of 11 children aged below 2 years of age, and 3 out of 9 in children above 2 years old. However there was no relationship between ages, mean pulmonary. Arterial pressure, hemoglobin, hematocrit, tricuspid regurgitation and proteinuria. There was not any relationship between proteinuria and the severity of pulmonary artery pressure, tricuspid 1-egurgitation, age and hematocrit in this group of children Significant proteinuria in children with acyanotic congential heart disease was present in 25% of cases [5 out of 20]. Nephrotic syndrome is uncommon in children with acyanotic pulmonary hypertension congenital heart disease