Evaluation of some biochemical changes in diabetic patients
Egyptian Journal of Hospital Medicine [The]. 2013; 50: 150-155
in English
| IMEMR
| ID: emr-170275
ABSTRACT
The present study consisted of 50 subjects were classified into three groups; Group [GI] Control group consisted of 10 clinically healthy adult subjects of both sexes free from any liver, kidney or cardiovascular diseases. Group [GII] diabetes mellitus type 1 consisted of 20 patients of both sexes. Group [GIII] diabetes mellitus type 1 with nephropathy consisted of 20 patients of both sexes. All subjects were undergo to the following investigated parameters; Ascorbic acid [vitamin C], Catalase, Total antioxidant capacity, Aldolase and Pyruvate kinase enzyme. vitamins C, catalase, total antioxidant capacity enzymes were highly significant decreased [P < 0. 01] in diabetes mellitus type 1 [GII] and diabetes mellitus type 1 with nephropathy [GIII] when compared to the control group. Adolase activity was highly significant increased [P < 0. 01] in diabetes mellitus type 1 with nephropathy [GIII] when compared to the control group. Pyruvate Kinase activity was highly significant increased [P < 0. 01] in diabetes mellitus type 1 [GII] when compared to the control group. The antioxidant and enzymes can be used for follow up in patients suffering from diabetes mellitus type 1 and predict other complications
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Ascorbic Acid
/
Pyruvate Kinase
/
Diabetes Mellitus, Type 1
/
Diabetes Mellitus, Type 2
/
Aldehyde-Lyases
/
Fructose-Bisphosphate Aldolase
/
Antioxidants
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Egypt. J. Hosp. Med.
Year:
2013
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