Effect of valve prosthesis - patient mismatch on short term outcome after aortic valve replacement

ABSTRACT

Small- size prostheses for aortic valve replacement can be too small in relation to the body size, thus causing valve prosthesis-patient mismatch [PPM] and abnormally high transvalvular pressure gradient. This study was planned to examine the relation between the PPM and the short term outcome after the operation. Baseline risk factors and short term outcome were analyzed in 23 patients, 19 [82.6%] males and 4[17.4%] females who underwent Aortic valve replacement. The indexed valve effective orifice area [IEOA] was estimated for each type and size of prosthesis implanted. PPM was defined as not clinically significant if patient IEOA is > 0.85 cm[2]/m[2] while clinically significant if patient IEOA is patients were divided into 2 groups, group "A" [9 patients with IEOA patients with IEOA > 0.85 cm[2]/m[2]]. There was no statistical difference between both groups regarding pre-operative patients' demographics. Operative characteristics were similar among patients in both groups with no statistical significance difference. ICU stay was 2.8 +/- 1.5 days in group A vs. 3.2 +/- 1.9 days in group B [p =0.08]. While total hospital stay was 12.5 +/- 9.8 days in Group A vs. 13.6 +/- 9.8 days in group B [p =0.59].The early mortality was encountered in two patients in group A and one patient in group B [p =0.59]. Prosthesis-Patient Mismatch has no significant effect on short term outcome in patients undergoing Aortic Valve Replacement