level of brain natriuretic peptide in patients with mitral stenosis before and after percutaneous balloon mitral valvuloplasty

ABSTRACT

The aim is to assess the plasma level of brain natriuretic peptide before and after percutaneous balloon mitral valvuloplasty in patients with mitral stenosis. The brain natriuretic peptide level was measured in 20 patients with rheumatic mitral stenosis and in another 20 age- and gender- matched healthy subjects as a control group. Patients with mitral stenosis underwent percutaneous balloon mitral valvuloplasty. Plasma brain natriuretic peptide level was measured before and after the procedure. The level of brain natriuretic peptide was found to be higher in patients with mitral stenosis [239.5 pg/ml] compared to the control group [15 pg/ml]. The level of brain natriuretic peptide was found to be reduced from 239.5 pg/ml to 162.75 pg/ml after percutaneous balloon mitral valvuloplasty. The level of brain natriuretic peptide was found to be reduced in patients with mitral stenosis after percutaneous balloon mitral valvuloplasty. This reduction was found to be correlated with the reduction in pulmonary artery systolic pressure [r=0.7] and the increase in the mitral valve area [r=0.55]