Synthesis and pharmacological studies of 1, 3-disubstituted malonic acids
Hamdard Medicus. 2005; 48 (4): 95-100
in English
| IMEMR
| ID: emr-171039
ABSTRACT
A new series of 1, 3-disubstituted malonic acid compounds [I-IX] were prepared via the reaction of malonyl di-chloride with the selected amino acids [P-alanine, glycine and aspartic acid] and their ethyl and propyl esters respectively. Structure of all the synthesized compounds have been elucidated by I.R. Synthesized compounds were found to be pharmacologically active and showed sedative-hypnotic activity and positive behavioral changes
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Index:
IMEMR (Eastern Mediterranean)
Language:
English
Journal:
Hamdard Med.
Year:
2005
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