[Effect of cervical mucus aspiration with insulin syringe on pregnancy rate in ART cycles]

ABSTRACT

A huge number of inefficient embryo implantation caused by embryo transfertechniques. Cervical mucus aspiration is the most important factor in successful embryo transfer.Based on reports pregnancy rate in woman with positive culture of cervical mucus is lower thanwomen with negative culture. Mucus plague on the catheter tip can cause improper embryoimplantation. This study evaluated the effect of cervical mucus aspiration on embryo transferresults.A Randomized Clinical trial study was performed on 340 women [in twogroups] by cycles of ART [Assisted reproductive technology] such as IVF [In vitro Fertilization] orICSI [Intra cytoplasmic sperm injection] referred to the Research and Clinical Center of Infertilityand Madar Hospital of Yazd. Male's and female's age, duration and cause of infertility were machedin two groups. The long time protocol was used for induction of the ovaries. In 170 patients, cervical mucus aspiration was done with insulin syringe [A or case group]. In the control group orgroup B [170 women], cervical mucus was aspirated only with cotton swabe. The patients werefollowed up by beta-HCG serum level measurement on the day 14 after embryo transfer. The datawere analyzed by Chi-square and t-test.Mean of men's age in group A was 35.26 +/- 5.2 years and in group B was 35.13 +/- 5.4 years.Mean of women's age in group A was 29.8 +/- 5.3 years and in group B was 30.2 +/- 5.4 years. Mean ofinfertility duration was 8.6 +/- 4.6 years in both groups. Mean of follicle number, oocytes number, embryos number, cause of infertility and IVF/ICSI method in both groups were similar and therewas no significant difference. Pregnancy rate in group A, was more than group B, [26.9% Vs19.2%], but was not statistically significant.Cervical mucus aspiration with insulin syringe before embryo transfer can increase thepregnancy rate. This has confirmed by other studies, so it seems that cervical mucus aspirationbefore embryo transfer is useful