lmmunofluorescen study of trophoblastic bound immunolglobuline G in preeclamptic women at term

ABSTRACT

The role of humoral immunity in the pathogenesis of PET is well known so that and that an altered immune response could be the cause of this disease. To evaluate the rue of placenta _ bound IgG in the pathogenesis of PET. 31 pregnant women were included in this study delivered by cesarean section at Baghdad Teaching Hospital. 16 of them were diagnosed and treated for PET. While the rest 15 cases Isere of normal women of using direct immunflorescnt test the level of IgG was detected. T the study showed a significant higher level of IgG in the placental biopsy. Of PET cases than those of control group using t-test. [P<0.025], Trophoblastic bound IgG plays an important role in the pathogenesis of PET as a part of altered humoral immune response against placental tissue in those patients