Placental morphological findings in hypertensive disorders of pregnancy

ABSTRACT

To study some morphological alterations in the placenta resulting from the effect of hypertensive disorder of pregnancy in a full term gestation. A prospective study of 50 placentas collected from hypertensive patients, and 50 from normotensive mothers, with term pregnancies and vaginal delivery of alive singleton, in hospitals, Alwahda[Aden] and Ibn khaldon- [Lahj], from March to September 1999. The mean weight for hypertensive placenta is 473.90grn, and for Normotensive is 606.04gm with mean diameter of15.12 cm and17.50 cm. For villous arteries, the mean in Normotensive was 1.37 msv and 1.69 msv for hypertensive, while the mean of illous veins for 0.405 msv for normotensive and 0.225 msv for hypertensive group. Infarcts were present in 100% and arteriosclerosis in 82% and syncytial knots in 98% of hypertensive placentas. Placentas of hypertensive patients has low weight and small diameter, reduced arterial lumen and increased in the wall thickness, increased venous lumen size and reduced in wall thickness. The study of the morphological alterations showed that the placentas of hypertensive patients characterized by the presence of infarctions, arteriosclerosis, and syncytial knots