[Consequences of early in the month of ramadan diabetic type 2 initially mal control]

ABSTRACT

Consequences of fasting in Ramadan on the metabolic control of previously poorly. Controlled diabetics are obvious but little described. We followed 20% type 2 diabetic patients with no known complications. They were receiving oral antidiuretic treatment and were poorly controlled with a HhAlc of 9, 6 +/- 2, 1%. They insisted on fasting even when advised not to do it. Clinical parameters, glycaemic and lipoproteins levels were evaluated three times 20-30 days before Ramadan, between 20 - 27 day in Ramadan and 20 days after the end of Ramadan. Fasting did not change their- weight nor there. Blood pressure. But it worsened the glycaemic control fasting glycemia increased by 2, l mmol/l [p < 0, 01] and fructosamine by 93 rmol/l [p < 0, 03]. However glycated hemoglobin remained unchanged. A 39% reduction in the HDL-cholesterol [p<0,003] was associated with a 24% increase in LDL cholesterol [p < 0, 02]. These parameters returned to their initial levels 20 days after the end of Ramadan. Ramadan, fasting may significantly worsen glycemic and lipoprotein control in initially poorly controlled type 2 diabetic patients