Gonadotrophic hypothalamic hypophyseal dysfunctions in men with liver cirrhosis

ABSTRACT

This work was carried out on 10 patients with liver cirrhosis and 4 normal controls matched for age and sex. The patients were diagnosed on the bases of clinical examination, liver function tests and abdominal ultrasonography. The results revealed higher basal levels of gonadotrophic hormones in patient group than normal controls. The level of gonadotrophic hormones measured half and one hour after stimulating with LHRH showed no significant difference between patients and controls. These data indicate that the pathophysiology of hypogonadism in men with liver cirrhosis may be a complex one