In vitro anti-proliferative effect of adiponectin on human endometriotic stromal cells through adiporl and adipor2 gene receptor expression

ABSTRACT

Background: Endometriosis is a complex disorder in reproductive age women which consist of stromal and epithelial cells implantation outside the uterine cavity. Adiponectin is a member of cytokine family with various metabolic roles and proliferation inhibition of many cancer cells. The aim of the present research was to determine adiponectin effect on human endometriotic stromal cells [ESCs] proliferation and their expression of adiponectin receptors