Serum level of selenium, IL-4, IL-10 and IFN-gamma in patients with allergic asthma, allergic rhinitis and healthy controls

ABSTRACT

Background: Allergic diseases have increased during the past decade I worldwide. Th2 type lymphocyte response is known to play an important j role in the process of allergic inflammation. IL-4, a mediator of type II I cytokine response increases IgE synthesis and Interferon gamma, a cytokirie I of type I response interferes with IL-4 and inhibits IgE production. Selenium j is an essential component of glutathione peroxides and changes in its plasma I level has been proposed to be associated with allergic diseases