Oral poliovirus vaccine in management of recurrent aphthous stomatitis

ABSTRACT

Back ground The most common cause of mouth ulcers is recurrent aphthous stomatitis [RAS]. There is no effective treatment for RAS and its exact etiology is obscure. One of the postulated causes is viral or bacterial infection and the role of herpes simplex virus was mentioned and treatment with Acyclovir reported to cause reduction in severity of disease. Oral polio virus vaccine [OPV] is reported to be effective in treatment of recurrent herpes simplex [RHS] According to our observation during recent years OPV not only is effective in management of RHS but also in some patient with concomitant RAS reduced its severity and frequency