Haemodynamic changes following cardio pulmonary bypass in mitral and aortic valve replacement under fentanyl anaesthesia

ABSTRACT

30 patients scheduled for valve replacement were selected, 20 underwent mitral valve replacement and 10 underwent aortic valve replacement under fentanyl anaesthesia. If we consider the haemodynamic changes following the discontinuation of cardio-pulmonary bypass in the mitral group, we find a highly significant drop in pulmonary capillary wedge pressure [PCWP] from 27.1-+6.5 to 18.3-+6, mean pulmonary artery pressure [MPAP] from 37.5-+11.4 for to 27.7-+8.9 systemic vascular resistance [SVR] from 1753.7-+423.3 to 1249-+229.9, highly significant rise in cardiac output [CO] from 3.3-+ 068 to 4.37-+068 and cardiac index [CI] from 2.1-+043 to 2.8-+03.9. In the aortic group no significant changes in the haemodynamic were noted