Comparison of three Escherichia coli Strains in recombinant production of reteplase
AJMB-Avicenna Journal of Medical Biotechnology. 2016; 8 (1): 16-22
in English
| IMEMR
| ID: emr-174771
ABSTRACT
Background:
Escherichia coli [E. coli] is the most extensively used host for the production of recombinant proteins. However, most of the eukaryotic proteins are typicallyobtained as insoluble, misfolded inclusion bodies that need solubilization and refolding. Reteplase as a highly disulfide-bonded recombinant protein is an example of difficult to express protein in E. coli
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Index:
IMEMR (Eastern Mediterranean)
Language:
English
Journal:
Avicenna J. Med. Biotechnol.
Year:
2016
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