Computational Detection of piRNA in Human Using Support Vector Machine
AJMB-Avicenna Journal of Medical Biotechnology. 2016; 8 (1): 36-41
in English
| IMEMR
| ID: emr-174774
ABSTRACT
Background:
Piwi-interacting RNAs [piRNAs] are small non-coding RNAs [ncRNAs], with a length of about 24-32 nucleotides, which have been discovered recently. These ncRNAs play an important role in germline development, transposon silencing, epigenetic regulation, protecting the genome from invasive transposable elements, and the pathophysiology of diseases such as cancer. piRNA identification is challenging due to the lack of conserved piRNA sequences and structural elements
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Index:
IMEMR (Eastern Mediterranean)
Language:
English
Journal:
Avicenna J. Med. Biotechnol.
Year:
2016
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