Intra-uterine insemination with superovulation in the treatment of male infertility

ABSTRACT

The value of intra-uterine insemination [IUI] coupled with Superovulation was studied in two groups of couples infertile because of male subfertility. IUI was carried out on 38 women during 78 treatment cycles after stimulation of ovulation with Clomid and human menopausal gonadotrophin [HMG] and on 29 women during 79 treatment cycles without stimulation. The pregnancy rate per patient [28.9%] and per treatment cycle [14.1%] was significantly higher in the stimulated group [p = 0.05 and p = 0.01, respectively]. This could be attributed to a significantly higher number of follicles recruited [p < 0.001], since there was homogeneity between the two groups for other confounding factors. It is concluded that Superovulation improves the pregnancy rate in couples with male subfertility treated with IUI