Infant leukemia

ABSTRACT

An eleven-month-old Bahraini infant girl, born full-term, vaccinated up-to-age, with normal milestone development; she was referred from King Hamad University Hospital [KHUH] with one-month history of high grade on and off fever associated with cough; her CBC showed anemia [7.4g/dl] and thrombocytopenia [30x109/L]. On examination, multiple bruises and small cervical lymph nodes were observed. CBC showed blasts [30%]. Bone marrow aspiration, flow cytometry and cytogenetic were sent for Mixed Lineage Leukemia [MLL] rearrangement. She was low risk; she received chemotherapy. This case was reported because of its rarity and up-to-date chemotherapy modalities which is linked to specific cytogenetic abnormality