Verification of ALDH activity as a biomarker in colon cancer stem cells-derived HT-29 cell line
Iranian Journal of Cancer Prevention. 2015; 8 (5): 27-34
in English
| IMEMR
| ID: emr-175777
ABSTRACT
Background:
Recent evidence has suggested that epithelial cancers including colorectal cancer [CRC] have driven by a small population of self-renewing, multi-potent cells termed cancer stem cells [CSCs] which could be responsible for recurrence of cancer. Aldehyde dehydrogenase 1 [ALDH1] activity has used as a functional stem cell biomarker to isolate CSCs in different cancers such as colorectal cancer
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Neoplastic Stem Cells
/
Biomarkers, Tumor
/
Cell Adhesion Molecules
/
HT29 Cells
/
Hyaluronan Receptors
/
Aldehyde Dehydrogenase
/
Retinal Dehydrogenase
/
Isoenzymes
/
Antigens, Neoplasm
Limits:
Humans
Language:
English
Journal:
Iran. J. Cancer Prevention
Year:
2015
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