Apoptosis/necrosis induction by ultraviolet, in ER positive and ER negative breast cancer cell lines
Iranian Journal of Cancer Prevention. 2015; 8 (6): 29-34
in English
| IMEMR
| ID: emr-175789
ABSTRACT
Background:
Ultraviolet [UV] light exposure has been one of the major inducers of apoptosis. UV exposure has caused pyrimidine dimers and DNA fragmentation which might lead to cell cycle arrest and apoptosis signals activation. UV induced apoptosis has investigated in MDA-MB 468 as an ER negative breast adenocarcinoma and MCF-7 as an ER positive breast cancer cell line. Apoptosis induction rate by UV might be different in these two types of cells due to different biological characteristics of the cell
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Ultraviolet Rays
/
Receptors, Estrogen
/
Apoptosis
/
Cell Line, Tumor
/
DNA Fragmentation
/
Necrosis
Limits:
Humans
Language:
English
Journal:
Iran. J. Cancer Prevention
Year:
2015
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