Effect of restraint street on serum electrolytes; in rats

ABSTRACT

Aim of this study was to determine the effect of immobilization stress on serum electrolytes [sodium, potassium, calcium and magnesium] in rats. Male albino wistar rats were used in experiment. Test animals were restrained by immobilizing for two hours on wire grids. Control animals were kept unrestrained in home cages. Rats were killed after the termination of restraint period. Blood was collected and serum separated for the analysis of electrolytes. Serum sodium, potassium and calcium were analyzed by flame photometer. Magnesium content was determined by spectrophotometer. Result shows a significant decreased [P = 0.001] in sodium, potassium, and calcium but increased [P = 0.001] in magnesium serum level. It is concluded that stress induced decrease in sodium, potassium and calcium and increase in serum magnesium level may contribute to stress induce hypertension