[Symptomatic hypertrophic cardiomyopathy in infants of diabetic mothers]

ABSTRACT

Hypertrocphic cardiomyopathy [HCM] in infants of diabetic mothers is characterized by asymmetric hypertrophy of the septum and interventricular walls. This affection is related to a transitional fetal hyper insulinism and is asymptomatic in most cases. Rarely HCM cause respiratory distress and congestive heart failure. Sometimes severe symptoms can be observed like asystolie and sudden fetal or neonatal death. The outcome of this disease is usually favorable with regression of myocardial hypertrophy. We report three cases of symptomatic cardimyopathy in infants of diabetic mothers diagnosed by echocardiography, all cases had favorable outcome with symptomatic treatment. We insist on the interest of the management of the diabetic mothers during pregnancy to reduce frequency and gravity of this disease and on the contribution of the echography to optimize the treatment