Incidence of ischemic heart disease in patients with type-II dependent diabetes mellitus

Hyperlipidemia appears to be a risk factor for atherogenesis. Diabetic patients have increased platelet adhesiveness and response to aggregating agents. These changes are also likely to favour atherogenesis. Patients with diabetes mellitus have a higher prevalence of atherosclerotic heart disease and ad higher incidence of myocardial infarction than the general population. To find out the incidence of IHD in patients with NIDDM and too evaluate the pattern of clinical presentation of IHD in diabetic patients like with typical/atypical symptoms, evidence of silent ischemia and myocardial infarction. This study was carried out in Nishtar Hospital, Multan from June 2004 to July 2005. A total of 100 patients were included in the study. Study design is non-probable purposes. The 100 patients selected for study were between 30-80 years old. Majority of them belonged to 30-45 years of age. Mean age was 48.7 +/- 11.2 years. History of disease duration was also noted and 100 patients included had disease from 1 month to 30 years. Out of 100 patients, 70 [70%] were male and 30 [30%] were female. Among these 17 had evidence of IHD. Typical symptoms of IHD were found in 6 patients. Majority of them had more than one symptom and in one patient, dyspnea was the only symptom. Moreover 5 patients [29.5%] of those who had IHD had dyspnea apart from other atypical symptoms. The incidence of IHD is higher in diabetic patients as compared to non-diabetics