Plasma cell leukemia

Plasma cell leukemia is a rare disorder. A case of 45 years old male, admitted with the complaints of generalized weakness, dizziness, recurrent epistaxis and swelling in front of his neck but not lymphadenopathy or hepatosplenimegaly. There were 24% plasma cells on peripheral film. Skeletal survey did not show any lytic lesions. Cell markers were positive for CD-38 but negative for CD-56. This favours the diagnosis of primary plasma cell leukemia