[Molecular exploration of the r91W [rPe65 gene] in Tunisian patients with early onset retinal Dystrophy and early onset retinis pigmentosa]

ABSTRACT

Background: Inherited retinal dystrophies are the major causes of blindness and visual impairment. Visual loss is due to neurosensory retinal and pigment epithelium cells degeneration. The most severe were Leber Congenital amaurosis [LCA], juvenile retinitis pigmentosa [RP] and early onset RP. The LCA and juvenile RP are called "Early Onset Retinal Dystrophy" [EORD]