Development of systemic lupus erythematosus following interferon-alpha therapy for hepatitis C infection
JCPSP-Journal of the College of Physicians and Surgeons Pakistan. 2016; 26 (3): 223-224
in English
| IMEMR
| ID: emr-177583
ABSTRACT
Interferon-alpha [IFN-alpha] therapy has been associated with de novo development of systemic lupus erythematosus [SLE]. We report a 48-year woman with chronic hepatitis C, who developed low grade fever, joint aches and pains, painful mouth ulcers, shortness of breath, dry cough and pleuritic chest pain after 2 months of completion of treatment with pegylated interferon-alpha. These clinical manifestations and the relevant immunologic investigations were in favour of SLE. She responded well to corticosteroids and hydroxychloroquine treatment
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Hepatitis C
/
Lupus Erythematosus, Systemic
Type of study:
Case report
Limits:
Female
/
Humans
Language:
English
Journal:
J. Coll. Physicians Surg. Pak.
Year:
2016
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