Vitamin D and respiratory disorder
Reviews in Clinical Medicine [RCM]. 2015; 2 (4): 195-199
in English
| IMEMR
| ID: emr-177650
ABSTRACT
The active form of vitamin D is synthesized in some body organs following sun exposure and dietary intake. Vitamin D exhibits its major and critical effects not only through regulation of calcium and phosphate metabolism but also by influencing on respiratory and immune system. Serum concentrations of 25-hydroxyvitamin D below the optimum limit lead to vitamin D insufficiency or maybe deficiency. These inappropriate concentrations of vitamin D lead to different types of pulmonary diseases such as viral and bacterial respiratory infection, asthma, chronic obstructive pulmonary disease, and cancer. In this review we described the association between vitamin D deficiency and severe therapy resistant asthma. We also reviewed the underlying molecular mechanism of vitamin D deficiency in children with severetherapy resistant asthma. Based on current information, future clinical trial are needed to study the role of vitamin D supplementation on different groups of patients with severe asthma including infants, children of school age, and ethnic minorities
Search on Google
Index:
IMEMR (Eastern Mediterranean)
Main subject:
Respiration Disorders
/
Asthma
/
Vitamin D Deficiency
/
Immunomodulation
Limits:
Humans
Language:
English
Journal:
Rev. Clin. Med.
Year:
2015
Similar
MEDLINE
...
LILACS
LIS