Effect of Body Mass Index on Intracytoplasmic Sperm Injection Outcomes

ABSTRACT

To determine the effects of increased BMI on ICSI outcomes. It was an analytical cross sectional study. Islamabad Clinic Serving Infertile Couples, Islamabad, Pakistan. Duration of the study was one year, from January 2013 to December 2013. Total of 150 females were classified into three groups on the basis of BMI. Those with BMI ranging from 18.5 - 24.9 kg/m2 /were placed in normal group [n=50], those with BMI ranging from 25 - 29.9 kg/m2/were placed in overweight group [n=50] and those with BMI ranging more than 30kg/ m2 were placed in obese group [n=50]. Serum levels of FSH, LH, Te, TSH, T3 and T4 were done in all three groups and their effects on oocyte and embryo quality were observed during controlled ovarian stimulation and after ICSI procedure. Obese group had significantly decreased ICSI outcomes due to increased levels of testosterone [p value< 0.05]. Increased BMI leads to decreased ICSI outcomes: