Resistant pattern of enterobacteriaceae isolates from surgical wards of tertiary care hospital

ABSTRACT

The objective of the study was to identify the species of enterobacteriaceae from the post operative patients and their susceptibility pattern. Rising antibiotic resistance rates among bacterial pathogens has resulted in increased morbidity and mortality. In Pakistan lack of infection control practice and non-existence of formal antibiotics policies has further augmented this problem. 200 postoperative wounds swabs were taken from different surgical and gynaeccolgy/obstetric wards of hospitals, specimens were then inoculated on Blood agar and MacConkey agar medium. The Enterobacteriaceac were identified by using battery of tests. Antimicrobial susceptibility was determined by Kirby Bauer disc diffusion method as per CLSI. E. coli isolates showed 100% resistance to ampicillin, while imepenem showed 94.3% sensitivity. Klebsiella species were found 100% resistant to ampicillin and 96.8% sensitive to imepenem. Enterobacteriaceae isolates show nearly the same type of multi-drug resistance even though some species showed 100% resistance to some antibiotics