Renal biopsy: a much needed tool in patients with Systemic Lupus Erythematosis [SLE]

ABSTRACT

Background and Objective: Systemic lupus erythematosis [SLE] is an inflammatory disorder associated with significant morbidity and mortality. Kidneys are frequently affected in SLE and various stages of lupus nephritis have been identified based on severity of the disease. Treatment varies with the staging and correct diagnosis is essential for timely intervention as it can have significant impact on morbidity and mortality.The objective of the study was to determine whether laboratory parameters of lupus nephritis [LN]; including urinalysis, serum creatinine [S. Cr] and 24 hours urine protein can accurately predict histologic staging of the disease