Investigation of Telomerase activity and hTERT gene expression in MCF7 cells treated with papaverine
Journal of Sabzevar University of Medical Sciences. 2013; 20 (2)
in Persian
| IMEMR
| ID: emr-180084
ABSTRACT
Introduction:
Telomere maintenance is essential for the continued proliferation of dividing cells, and is implicated in chromosome stability and cell immortalization. Telomerase activity, that allows cancer cells to maintain their telomeric DNA for an indefinite replicative capacity, is an attractive target against cancer. A well known benzylisoquinoline alkaloid, papaverine, we focused on to evaluate its antiproliferaive effects on breast cancer MCF7 cells
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Index:
IMEMR (Eastern Mediterranean)
Language:
Persian
Journal:
J. Sabzevar Univ. Med. Sci.
Year:
2013
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