Acute effects of swimming exercise on withdrawal syndrome sign in morphine-dependent rats

ABSTRACT

Background: Aerobic exercise stimulates the release of beta- endorphin and other endogenous opioid peptides that are induced influences of morphine and other receptors agonist's opioid peptides. Therefore, it may be reduced withdrawal sign and benefit in withdrawal period. The purpose of this study was investigated acute effects of swimming exercise on common behavior following withdrawal syndrome in morphine-dependent rats