Stable down-regulation of HLA class-I by serum starvation in human PBMCs

Mahsa, Rahmani; Hamid Reza, Khorasani; Monireh, Golpour; Ali Shabestani, Monfared; Hosein, Nattaj; Saeeid, Abedian; Amrollah, Mostafazadeh.

IJI-Iranian Journal of Immunology. 2016; 13 (1): 54-63

in English | IMEMR | ID: emr-180322

ABSTRACT

Background:

the human leukocyte antigen [HLA] matching between organ donor and recipient is an acceptable strategy in clinical transplantation since 1964. However, in bone marrow transplantation, finding matched donors is often problematic. Thus new method for down regulation of HLA can be an alternative strategy to solve this

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Index: IMEMR (Eastern Mediterranean) Language: English Journal: Iran. J. Immunol. Year: 2016

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Index: IMEMR (Eastern Mediterranean) Language: English Journal: Iran. J. Immunol. Year: 2016