[Squamous cell carcinoma of the gallbladder]

ABSTRACT

Squamous cell carcinoma [SCC] of the gallbladder is responsible for 0 to 12,7% of malignant neoplasms of this organ. The histogenesis and the mechanism of involved are controversial and prognosis is not clearly established. We report four cases of epidermoid carcinoma, three women and one man that the mean age was 62 year. The diagnosis of malignancy was suspected in preoperative period in three patients. Two tumours were localised in the gallbladder [T2] without metastasis and treated with cholecystectomy and irradiation in one patient. The last is alive without recurrence with a follow up of 7 years. The former had a recurrence after 8 months. The others patients were in stage T4 with invasion of adjacent organs without metastasis. The treatment consisted of cholecystectomy and resection of involved organs with regional lymphadenectomy and chemotherapy in one patient. Those patients were died 4 months and 6 months after surgery