Evaluating the effect of midodrine on renal resistance index in patients with liver cirrhosis and ascites
AAMJ-Al-Azhar Assiut Medical Journal. 2016; 14 (1): 19-23
in English
| IMEMR
| ID: emr-181350
ABSTRACT
Background:
Portal hypertension, which occurs as a consequence of liver cirrhosis, leads to splenic vasodilatation and alterations in the systemic circulation. Arterial vasodilatation in the splanchnic circulation appears to play a central role in hemodynamic changes and in the decline in renalfunction in cirrhosis. Peripheral vasodilatation, which occurs as a part of alterations in the systemic circulation, may decrease the renal blood flow and subsequently raise plasma renin activity. Midodrine is a agonist and acts as a peripheral vasoconstrictor; therefore, it may reduce plasma renin activity and improve renal function
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Index:
IMEMR (Eastern Mediterranean)
Language:
English
Journal:
Al-Azhar Assiut Med. J.
Year:
2016
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