effect of hemodialysis on Q-T interval on children with chronic renal failure

ABSTRACT

The hemodialysis patients have a wide variety of electrocardiographic [ECG] abnormalities and, in certain instances; hemodialysis itself seems to be a cause of ECG changes and different kinds of dysrhythmias. The purpose of the study was to assess the effect of hemodialysis on QT and corrected QT [QTc] interval and QTc interval dispersion in patients with end-stage renal failure 10 min before [pre-HD] and 10 min after each hemodialysis [post-HD]. An observational cross-section study was conducted on 30 patients 'admitted to the dialysis unit in Abou El Ressh pediatric hospital along a period of 6 months starting from October 2008. The total number of cases on regular hemodialysis throughout the year was 60 cases. 30 cases were picked at random to be included in the present work. Clinical examination, history taking and laboratory analysis were offered to all patients, 12 lead ECG was done before and after hemodialysis. The results showed that after hemodialysis there were significant changes for the QTc and QT dispersion with 3.3% of cases had prolonged QT interval after hemodialysis and 43.3% had prolonged QTc after dialysis and 50% had abnormal QTd after dialysis. After dialysis there was significant negative correlation between Na level and QTc, also between K level and QTc