role of metal ions on the pharmacological properties of herbal drugs used as antibacterial agents

ABSTRACT

Various cobalt [II], copper [II], nickel [II] and zinc [II] metal complexes of citrullus and cuminum cyminum plant extract have been synthesized and screened against a number of bacterial species such as streptococcus pyogenes, escherichia coli, bacillus tuberculi, gonococcus, pseudomonas aeruginosa and bacillus subtilis. The pharmacological assay show the metal complexes to be more potent antimicrobials than the pure plant extract