lnterleukin-6 polymorphisms and risk of coronary artery diseases in a Chinese population: a case-control study

ABSTRACT

Objective: We aimed to evaluate the relationship between /L-6-174G>C, -572G>C and -597G>A polymorphisms and development of coronary artery diseases in a Chinese population. Methods: A total of 275 patients with coronary artery disease and 296 healthy control subjects were collected between January 2013 and November 2014. The IL-6 genotyping for -174G>C, -592G>C and -597G>A polymorphic sites was determined by polymerase chain reaction-restriction fragment length polymorphism [PCR-RFLP] according to the manufacturer instructions