[Another look at the cases of Mucormycosis at Emam Reza hospital]

ABSTRACT

Mucormycosis or Zygomycosis is a rare opportunistic and fulminated fungal infection with high mortality. It occurs most often in diabetic and immuno-compromised patients, including those with hematological malignancy. There are several forms of disease that rhinocerebral is the most common form. Early diagnosis plays an important role in prognosis of the disease. Since, previous papers were mainly focused on pathologic aspects and case reports, we decided to review the cases on the basis of etiologic agents, predisposing factors, Clinical signs on admission and the role of early diagnosis in golden time on prognosis. This is a retrospective and cross sectional study of 18 cases of approved Mucormycosis that diagnosed in Imam Reza hospital during 12 years during 1312-1384. In addition to those, four recent cases studied prospectively. The study population was 15 men and 7 women. The cases were from 1 to 80 years old. Diabetes mellitus was the most common Predisposing factor [54.4%]. Most of the cases were rhinocerebral form. Mortality rate was more than 75%. Prognosis was good in less than 25% of the cases who received early diagnosis and treatment. Early diagnosis and correct Treatment [surgical and medical intervention] are critical because they could improve the prognosis for survival