[ adult onset still's disease. 11 cases]

ABSTRACT

The stills' disease of the adult is a systemic disease that the couse is unknown. If the pediatric forms are frequent, the affection of the adult is rare and it's diagnosis is difficult. The purpose of this study is to analysis the clinical and evaluative features of the adult still's disease and to compare our results with the literature it is retrospective study about 21 years that permitted to collect 11 cases according the criteria of yamaguchi. It is matter of 6 men and 5 women that the mean age is 31 years old [age range 16 to 48 years old] the fever was constant. The skin rash noticed in 8 patients [72.7%] a polyarthritis was noticed in all the patients. Chronic in 10 cases [90.9%] which 2 erosion forms adenopathies were present in 5 patients, a splenomegaly and hepatomegly were noticed respectively in 4 and 2 cases. Inflammation syndrome with hyperleukocytosis was constant - and a hepatic cytolysis was noticed in 80% the total ferritinemia titrated in 8 patients was constantly high. The hemocultures realized in all the patients were sterile and the complete immunology examination was negative. The strong dose of corticoid was prescrited with sucess in all the patients. The immediate evolution was favourable in 10 patients. We depolore one death after astate of deep denutrution. The still's disease of the adult is rare, it's diagnosis is difficult, sensible to the corticotherapy and it's clinicoevolution aspect in our country is comparable to the literature