Melatonin pretreatment enhances the homing of bone marrow-derived mesenchymal stem cells following transplantation in a rat model of liver fibrosis

Keywan, Mortezaee; Parichehr, Pasbakhsh; Iraj Ragerdi, Kashani; Fatemeh, Sabbaghziarani; Ameneh, Omidi; Adib, Zendedel; Soudabeh, Ghasemi; Ahmad Reza, Dehpour.

IBJ-Iranian Biomedical Journal. 2016; 20 (4): 207-216

in English | IMEMR | ID: emr-182876

ABSTRACT

Background:

Bone marrow-derived mesenchymal stem cells [BMMSCs] transplantation has been considered as a promising milestone in liver fibrosis treatment. However, low amounts of homing are a major obstacle. We aimed to investigate the role of melatonin pretreatment in BMMSC homing into experimental liver fibrosis

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Index: IMEMR (Eastern Mediterranean) Language: English Journal: Iran. Biomed. J. Year: 2016

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Index: IMEMR (Eastern Mediterranean) Language: English Journal: Iran. Biomed. J. Year: 2016