Autophagy-modulated human bone marrow-derived mesenchymal stem cells accelerate liver restoration in mouse models of acute liver failure
IBJ-Iranian Biomedical Journal. 2016; 20 (3): 135-144
in English
| IMEMR
| ID: emr-182883
ABSTRACT
Background:
Mesenchymal stem cells [MSCs] have been recently received increasing attention for cell-based therapy, especially in regenerative medicine. However, the low survival rate of these cells restricts their therapeutic applications. It is hypothesized that autophagy might play an important role in cellular homeostasis and survival. This study aims to investigate the regenerative potentials of autophagy-modulated MSCs for the treatment of acute liver failure [ALF] in mice
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Index:
IMEMR (Eastern Mediterranean)
Language:
English
Journal:
Iran. Biomed. J.
Year:
2016
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