Inverse association of plasma level of glutathione peroxidase with liver fibrosis in chronic hepatitis B: potential role of iron
Middle East Journal of Digestive Diseases. 2016; 8 (2): 122-130
in English
| IMEMR
| ID: emr-183027
ABSTRACT
Background:
Oxidative stress plays a major pathogenic role in liver injury following chronic hepatitis B. Glutathione peroxidase [Gpx] has a central role in regulating the oxidative state. Hepatitis B virus [HBV] results in down-regulation of Gpx. On the other hand, iron homeostasis is disrupted in HBV infected patients. Therefore, the objective of this study was to assess the interplay of Gpx and serum iron on clinical and virological characteristics of patients with chronic HBV infection
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Index:
IMEMR (Eastern Mediterranean)
Language:
English
Journal:
Middle East J. Dig. Dis.
Year:
2016
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