In vitro effect against some types of cancer using turmeric powder

ABSTRACT

Tumeric is a perennial herb and member of Zingiberaceae [ ginger] family. The portion of the plant used as a yellow powder which is used as a flavor in many cuisines and as a traditional medicine to treat some diseases. In this study the cytotoxic activity of Turmeric against human liver tumor cell lines [HEPG2], colon carcinoma [HCT] and tumor breast carcinoma [MCF7] were evaluated. Total phenols contents [TPC] and fractionation of poly phenolic and flavonoids compounds in turmeric were determined. The scavenging effect of DPPH [2,2- diphenyl-1-picrylhydrazyl] radicals was evaluated. The organoleptic properties of wheat pie was tested with different levels [0%,5%,10% and 15%] of tumeric powder. The results showed that turmeric exhibited an efficient cytotoxicity against HEPG2, MCF7 and HCT carcinoma cell lines ; moreover turmeric extracts possess significant antioxidant properties and is rich in phenolic compound. Crust color in pie containing turmeric powder become darker, and it varied with increasing the quantity of turmeric powder. Substitution of wheat flour with 5% turmeric powder showed acceptable sensory scores comparable to wheat pie. Pie containing turmeric powder can be considered as a health-promoting functional food