In vitro enzymatic investigation of Ficus carica [Fruit]

ABSTRACT

The present study demonstrates the biological study of Ficus carica fruit. Methanolic extract of plant fruit was prepared and evaporated under reduced pressure by rota vapor and n- hexane, Chloroform, ethyl acetate and n-butanol soluble fractions were prepared separately from crude methanolic extract. These fractions were then screened for acetyl cholinesterase, butryl cholinesterase and lipoxygenase activities. n-butanol soluble fraction showed significant antiacetylcholinesterase activity [78.55+/-0.76%] with IC[50] of 55.8+/-0.37[micro]g/ml, ethyl acetate soluble fraction showed significant anti-butrylcholinesterase activity [70.35+/-0.85%] with IC[50] of 276.5+/-0.64[micro]g/ml and significant antilipoxygenase activity was shown by ethyl acetate soluble fraction [62.52+/-0.26%] with IC[50] of 380+/-0.08[micro]g/ml