[An in vitro study of the effect of sodium selenite on telomere length and telomerase activity of bone marrow stromal cells in aged rats]

ABSTRACT

Background and Aim: the number and potential of proliferation and differentiation of bone marrow mesenchymal stromal cells decreases with age. These changes reduce efficacy of autologous transplantation in old people. The purpose of this study was to evaluate the effect of sodium selenite on telomere length and telomerase activity of bone marrow stromal cells [BMSCs] in aged rats