Susceptibility of common bacterial isolates to ceftriaxone

ABSTRACT

The in vitro antibacterial activity of ceftriaxone has been determined among 1060 strains of organisms isolated from patients attending our hospital. All sensitive strains showed wide zones of inhibition by disc susceptibility testing. No strains were encountered which were resistant to ceftriaxone but sensitive to either cefuroxime or cefotaxime. The broad spectrum of activity of the antibiotic has been confirmed for our locality. This finding together with its exceptionally long half-life and ease of administration [single daily dosage] warrants clinical studies to confirm its efficacy in serious infections and surgical prophylaxis