Solid lipid nanoparticles: an emerging novel drug delivery system

ABSTRACT

The solid lipid nanoparticles [SLNs], a type of lipid nanoparticles [LNPs], is a special field of interest that has emerged during the last few decades as a potential colloidal carrier delivery system. They have gained great attention in controlling the drug release, increasing the bioavailability and attaining a sustain release profile of entrapped drug substance with fewer side effects as compared to traditional dosage forms. They serve as a promising system in various pharmaceutical fields such as cosmetics, research, clinical medicine and other allied sciences. SLNs have also been identified as a substitute to carrier systems such as liposomes, emulsions and polymeric nanoparticles. In the present review, the structure, advantages and applications of SLNs are focused which would provide an idea of global scenario of SLNs