Differential Expression and Localization of Nanog, Oct 3/4 and C-Kit in Mouse Ovarian Tissue According to Age

ABSTRACT

Objective: To investigate the expression of embryonic/ pluripotent stem cell markers including Nanog, Octamer - Binding Protein [Oct 3/4] and c-Kit from the newborn to aging period in the ovary tissues of mouse. Design: Experimental study using mouse ovary tissues. The expression and localization of Nanog, Oct 3/4 and c-Kit expression were studied in newborn, pubertal, adult and aging ovary. Setting: Department of Histology and Embryology, Pamukkale University, School of Medicine, Turkey