Small cell carcinoma of the ovary hypercalcemictype [SCCOHT]: a rare case after in vitro fertilization

ABSTRACT

Small cell carcinoma of the ovary, hypercalcemic type [SCCOHT] is a very rare and lethal tumor, mostly affecting young women, with aggressive clinical course. It has a worse prognosis in younger women and most of them died within two years of diagnosis. We are reporting a unique case of SCCOHT in a 35 years old, nulliparous lady with primary infertility in which symptomatic hypercalcemia was a presenting feature of her cancer. She was completely healthy before third cycle of IVF. Within two months of her third IVF cycle, she developed SCCOHT with a very rapid and aggressive course of disease and fatal outcome. Patient died within one month of her first symptom presentation [3 months after IVF cycle]